Results Page

Status:

Task completed successfully.

Submission info:

Results:

Template selection:

Template ClustalW2 Score Identity Global Similarity Selected View Download human opioid 12 (_ et al., 2018) 6B73_A 26 23.364 0.209 View Download human opioid tructure of the human kappa-opioid receptor in complex with JDTic (Wu et al., 2012) 4DJH_A 25 23.529 0.202 View Download human beta-adrenergic beta2AR-T4L - CIM (Ma et al., 2017) 5D6L_A 25 22.981 0.189 View Download human beta2-adrenergic 'High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.' (Cherezov et al., 2007) 2RH1_A 25 22.981 0.188 View Download human opioid Structural basis for bifunctional peptide recognition at human delta-opioid receptor. (Fenalti et al., 2015) 4RWD_A 25 23.676 0.182 View Download human beta-adrenergic Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation. (Staus et al., 2016) 5JQH_A 24 22.981 0.187 View Download mouse opioid Structure of the delta opioid receptor bound to naltrindole (Granier et al., 2012) 4EJ4_A 25 22.741 0.183 View Download human opioid Molecular control of delta-opioid receptor signalling. (Fenalti et al., 2014) 4N6H_A 25 23.676 0.177 View Download human opioid Structural basis for bifunctional peptide recognition at human delta-opioid receptor. (Fenalti et al., 2015) 4RWA_A 25 22.741 0.18 View Download human nociceptin The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. (Miller et al., 2015) 5DHH_A 25 22.257 0.18 View Download human nociceptin The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. (Miller et al., 2015) 5DHG_A 25 22.257 0.178 View Download human nociceptin Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. (Thompson et al., 2012) 4EA3_A 25 21.944 0.178 View Download mouse opioid Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist. (Manglik et al., 2012) 4DKL_A 24 21.184 0.179 View Download turkey beta1-adrenergic 'Structure of a Beta1-Adrenergic G-Protein-Coupled Receptor.' (Warne et al., 2008) 2VT4_B 24 21.739 0.177 View Download human dopamine 'Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.' (Chien et al., 2010) 3PBL_A 27 21.231 0.155 View Download turkey beta-adrenergic Ligand occupancy in crystal structure of Beta1 adrenergic G protein coupled receptor (Leslie et al., 2015) 5F8U_A 24 21.739 0.174 View Download human angiotensin-AT2R Structural Basis for Selectivity and Functional Diversity in Angiotensin II Receptors (Zhang et al., 2017) 5UNG_B 23 21.148 0.156 View Download bovine rhodopsin Crystal structure of metarhodopsin II. (Choe et al., 2011) 3PQR_A 22 20.059 0.146 View Download human angiotensin-AT1R Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. (Zhang et al., 2015) 4YAY_A 23 19.697 0.145 View Download human chemokine_CXC Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. (Qin et al., 2015) 4RWS_A 23 20.0 0.136 View Download bovine rhodopsin 'The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure' (Okada et al., 2004) 1U19_A 22 19.492 0.143 View Download human adenosine Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket. (Sun et al., 2017) 5UIG_A 24 19.938 0.107 View Download human chemokine_CC Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. (Zheng et al., 2016) 5T1A_A 24 18.845 0.125 View Download human angiotensin-AT1R Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. (Zhang et al., 2015) 4ZUD_A 23 18.485 0.129 View Download human histamine 'Structure of the human histamine H1 receptor complex with doxepin.' (Shimamura et al., 2011) 3RZE_A 22 18.38 0.131 View Download human chemokine_CC Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. (Tan et al., 2013) 4MBS_A 20 18.541 0.129 View Download human chemokine_CC Intracellular allosteric antagonism of the CCR9 receptor. (Oswald et al., 2016) 5LWE_A 22 18.976 0.116 View Download human adenosine Structural basis for allosteric regulation of GPCRs by sodium ions. (Liu et al., 2012) 4EIY_A 23 19.033 0.1 View Download human adenosine 'The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist.' (Jaakola et al., 2008) 3EML_A 22 19.444 0.099 View Download human purinergic_P2Y1 Two disparate ligand-binding sites in the human P2Y1 receptor (Zhang et al., 2015) 4XNW_A 20 17.91 0.127 View Download human endothelin Activation mechanism of endothelin ETB receptor by endothelin-1. (Shihoya et al., 2016) 5GLI_A 19 18.659 0.12 View Download human muscarinic Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. (Haga et al., 2012) 3UON_A 21 17.901 0.124 View Download human protease-activated Structural insight into allosteric modulation of protease-activated receptor 2. (Cheng et al., 2017) 5NDD_A 19 18.266 0.122 View Download human adenosine Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength. (Segala et al., 2016) 5IU4_A 23 18.731 0.094 View Download human cannabinoid Crystal Structure of the Human Cannabinoid Receptor CB1. (Hua et al., 2016) 5TGZ_A 20 18.944 0.098 View Download human purinergic_P2Y1 Two disparate ligand-binding sites in the human P2Y1 receptor (Zhang et al., 2015) 4XNV_A 20 17.612 0.122 View Download rat muscarinic Structure and dynamics of the M3 muscarinic acetylcholine receptor. (Kruse et al., 2012) 4DAJ_A 25 17.593 0.118 View Download human endothelin Activation mechanism of endothelin ETB receptor by endothelin-1. (Shihoya et al., 2016) 5GLH_A 19 17.595 0.119 View Download human adenosine Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity. (Glukhova et al., 2017) 5UEN_A 20 17.523 0.087 View Download human purinergic_P2Y12 Structure of the human P2Y12 receptor in complex with an antithrombotic drug (Zhang et al., 2014) 4NTJ_A 19 16.82 0.082 View Download human cannabinoid High-resolution crystal structure of the human CB1 cannabinoid receptor. (Shao et al., 2016) 5U09_A 17 17.391 0.077 View Download human purinergic_P2Y12 Agonist-bound structure of the human P2Y12 receptor (Zhang et al., 2014) 4PY0_A 17 16.768 0.074 View Download human sphingosine Crystal structure of a lipid G protein-coupled receptor. (Hanson et al., 2012) 3V2Y_A 19 16.918 0.051 View Download human purinergic_P2Y12 Agonist-bound structure of the human P2Y12 receptor (Zhang et al., 2014) 4PXZ_A 18 16.717 0.069 View Download human lysophosphatidic-acid Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. (Chrencik et al., 2015) 4Z35_A 18 14.894 0.055 View Download human lysophosphatidic-acid Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. (Chrencik et al., 2015) 4Z34_A 18 14.759 0.055 View Download human lysophosphatidic-acid Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. (Chrencik et al., 2015) 4Z36_A 18 14.894 0.053 View Download human glucagon-like Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators (Song et al., 2017) 5VEX_A 16 11.285 -0.021 View Download human corticotropin Structure of class B GPCR corticotropin-releasing factor receptor 1. (Hollenstein et al., 2013) 4K5Y_A 12 11.599 -0.013 View Download human glucagon-like Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. (Song et al., 2017) 5VEW_A 16 11.285 -0.021 View Download human corticotropin Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures (Dore et al., ?) 4Z9G_A 11 11.912 -0.024 View Download human glutamate5 Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain. (Dore et al., 2014) 4OO9_A 13 9.907 -0.04 View Download human glucagon-like Crystal structure of the GLP-1 receptor bound to a peptide agonist. (Jazayeri et al., 2017) 5NX2_A 11 9.346 -0.024 View Download human glutamate5 Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile). (Christopher et al., 2015) 5CGC_A 12 9.538 -0.042 View Download human glutamate5 Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile). (Christopher et al., 2015) 5CGD_A 12 9.231 -0.042 View Download rabbit glucagon Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. (Zhang et al., 2017) 5VAI_R 10 9.133 -0.034 View Download human glucagon Extra-helical binding site of a glucagon receptor antagonist. (Jazayeri et al., 2016) 5EE7_A 8 8.411 -0.032 View Download human glucagon Structure of the human glucagon class B G-protein-coupled receptor. (Siu et al., 2013) 4L6R_A 6 9.657 -0.047 View Download human glutamate1 Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator (Wu et al., 2014) 4OR2_A 8 7.385 -0.068 View Download human glucagon Structure of the full-length glucagon class B G-protein-coupled receptor. (Zhang et al., 2017) 5XF1_A 7 7.042 -0.058 View Download human glucagon Structure of the Full-length glucagon class B G protein-coupled receptor (Zhang et al., 2017) 5XEZ_A 7 7.042 -0.058 View Download human smoothened Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. (Wang et al., 2014) 4QIM_A 7 6.266 -0.092 View Download human smoothened Structure of the human smoothened receptor bound to an antitumour agent. (Wang et al., 2013) 4JKV_A 7 6.486 -0.1 View Download human smoothened Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. (Weierstall et al., 2014) 4O9R_A 7 6.166 -0.089 View Download human smoothened Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. (Wang et al., 2014) 4QIN_A 7 6.216 -0.098 View Download human smoothened Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. (Wang et al., 2014) 4N4W_A 6 6.199 -0.101 View Download human smoothened_N-domain Structural basis of Smoothened regulation by its extracellular domains. (Byrne et al., 2016) 5L7I_A 8 4.545 -0.103 View Download

Download table

Alignments generated with selected templates:

Template Alignment Method Identity Global Similarity Non-anchored alignment Anchored Alignment Non-anchored Alignment Anchored Alignment Selected human opioid 12 (_ et al., 2018) 6B73_A profile-profile 22.393 0.194 View View Download Download human opioid 12 (_ et al., 2018) 6B73_A multiple SA 23.364 0.209 View View Download Download human opioid 12 (_ et al., 2018) 6B73_A simple pairwise SA 23.364 0.204 View View Download Download human opioid tructure of the human kappa-opioid receptor in complex with JDTic (Wu et al., 2012) 4DJH_A profile-profile 22.936 0.202 View View Download Download human opioid tructure of the human kappa-opioid receptor in complex with JDTic (Wu et al., 2012) 4DJH_A multiple SA 23.22 0.205 View View Download Download human opioid tructure of the human kappa-opioid receptor in complex with JDTic (Wu et al., 2012) 4DJH_A simple pairwise SA 22.601 0.197 View View Download Download

Download table

Thank you for using GPCRM Structure Modelling Server!

Any questions? Contact us: support|biomodellab.eu

University of Warsaw & The International Institute of Molecular and Cell Biology

support|biomodellab.eu

Terms of Use

© Copyright - BIOmodeling, All Rights Reserved.