GPCRM web service

A web service to predict structures of G-protein-coupled receptors (GPCRs) using advanced homology modeling tools: profile-profile alignment, multiple structural templates, and Z coordinate-based filtering of resulting models. Two distinct loop modeling techniques are employed - Modeller and Rosetta - and the proper scoring is used to score the final ranking list of GPCR models.

      E-mail address is optional. You could submit your e-mail address to receive the link to the results for further usage.
            To improve accuracy of the alignment and model building provide the suggested S-S bridge between the extracellular loop 2 and the transmembrane helix III.
              Cys 1:     Cys 2:

                      Please, avoid including a lysozyme sequence in your query.

                              Last update: January 2018.

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